Publications by authors named "D S Yamashita"
Extensive neovascularization is a hallmark of glioblastoma (GBM). In addition to supplying oxygen and nutrients, vascular endothelial cells provide trophic support to GBM cells via paracrine signaling. Here we report that Endocan (ESM1), an endothelial-secreted proteoglycan, confers enhanced proliferative, migratory, and angiogenic properties to GBM cells and regulates their spatial identity.
View Article and Find Full Text PDFIntravascular accumulation of atypical large lymphoid cells is a rare condition that necessitates a differential diagnosis of intravascular lymphoma (IVL). Recently, a non-neoplastic condition known as benign atypical intravascular CD30+ T-cell proliferation (BAITP) has been identified. This condition is characterized by CD30+ and CD3+ or CD4+ atypical T-cells and is often associated with trauma and chronic inflammation.
View Article and Find Full Text PDFBackground: Cholesterol embolism causes various organ dysfunctions, including skin, kidney, and gastrointestinal tract dysfunction, as well as immunological abnormalities, such as hypocomplementemia and eosinophilia. However, only a few cases of vasculitis accompanied by cholesterol embolism have been reported.
Case Presentation: We present the case of an 82-year-old man with cholesterol embolism who also developed small-vessel vasculitis of the skin and muscles.
Article Synopsis
- Upstaging to pT3a after partial nephrectomy for cT1 renal cell carcinoma (RCC) is uncommon, occurring in 3.6% of cT1a and 19% of cT1b patients within a study of 389 cases from 2011-2022.
- The median tumor size for upstaged cases was 43 mm, and during a 59-month follow-up, there were six recurrence events, highlighting a significant risk for those with Fuhrman grade ≥3.
- Five-year survival rates were reported as 75.7% for metastasis-free survival, 96.2% for cancer-specific survival, and 88.1% overall, indicating
Right bundle branch block can occasionally occur when a guide wire or catheter is inserted into the heart. An 83-year-old woman with preexisting left bundle branch block (LBBB) was diagnosed with paroxysmal atrial fibrillation (PAF) and severe mitral regurgitation (MR). The patient was started on amiodarone (100 mg/day) and bisoprolol (1.
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