Intraepithelial lymphocytes in relation to NIH category IV prostatitis in autopsy prostate.

Background: Quantitative analysis of the number, normal and pathologic ratios between lymphocytes and epithelial cells (ECs), and the significance of intraepithelial lymphocytes (IELs) in normal prostatic epithelium, benign prostatic hyperplasia (BPH), and high grade prostatic intraepithelial neoplasia (PIN) in relation to NIH category IV prostatitis (histologic prostatitis: HP) was studied in autopsy prostate.

Methods: IELs were analysed in 59 autopsy prostates, which was routinely embedded in paraffin and immunohistochemically stained for CD3. An average of 300-500 ECs were counted per case.

Protein and mRNA levels of YKL-40 in high-grade glioma.

Malignant gliomas are the most common type of primary malignant brain tumours, characterized by extreme proliferation and aggressive invasion. There is evidence for over-expression of the YKL40 gene in high-grade gliomas. The high serum levels of the glycoprotein are associated with poor prognosis of various inflammatory and tumour processes.

[Two autopsy cases with microchimerism].

Identification of chorionic villi in spiral arterioles and later in maternal circulation is known as maternal microchimerism. Distant consequences of this condition are unclear associated mainly with risk from autoimmune diseases. Our presentation is aiming at introducing the term microchimerism and to propose a connection between this phenomenon and the reasons for the death of the fetus.