Transbronchial Lung Cryobiopsy for Diagnosis of Pediatric Interstitial Lung Disease.

Background: Tissue diagnosis of Childhood interstitial lung diseases is of paramount importance to outline management.

Case Characteristics: A 10-year-old boy with prolonged cough, and computed tomography of thorax with features suggestive of primary Langerhans's cell histiocytosis.

Intervention: Transbronchial cryobiopsy of lung using flexible cryoprobe, revealed a final diagnosis of Surfactant protein C/ABCA3 deficiency.