What is the Role of Measuring Urinary Gluten Immunogenic Peptides in Clinical Practice in Patients with Coeliac Disease?

Background And Aims: In coeliac disease, the clinical role of the urinary gluten immunogenic peptide is unclear. It has been suggested it can be a non-invasive marker of villous atrophy. Therefore, we present the largest cross-sectional clinical data in patients with coeliac disease to establish the diagnostic accuracy of the urinary gluten immunogenic peptide in identifying villous atrophy.

One Year of Gluten Free Diet Impacts Gut Function and Microbiome in Celiac Disease.

Background & Aims: Currently, the main treatment for celiac disease (CD) is gluten free diet (GFD). This observational cohort study investigated the impact of CD and 1 year of GFD on gut function and microbiome.

Methods: 36 newly diagnosed patients and 36 healthy volunteers (HVs) were studied at baseline and at 12 months follow up.

The Midline Lateral Parapatellar Arthrotomy: A Safe Alternative Approach for Lateral Tibial Plateau Fractures.

Objectives: The midline lateral parapatellar (LP) approach has been shown in a cadaveric study to provide superior articular exposure compared to the anterolateral approach (AL). The purpose of this study was to report on outcomes and complications with the LP approach.

Methods: Design: Retrospective comparative cohort study and prospective cohort.

Caring for Underserved Populations in Orthopedic Trauma.

Contemporary care of patients with orthopedic trauma is complex from surgical, cultural, administrative, financial, and linguistic perspectives. Surgeons must understand patients' backgrounds and resources to have an idea of the manner in which care can be delivered most effectively. Recognizing patients from traditionally underserved or vulnerable groups will help the surgeon to individualize their approach to the care of each individual patient.

Celiac disease care differs significantly between high- and low-middle-income countries: a global survey of celiac experts from 63 countries.

Background And Aim: Celiac disease (CeD) is increasingly diagnosed but significant disparities exist in awareness, practices, resources, and legislation worldwide. We conducted a global online survey with CeD experts to assess this disparity internationally.

Methods: A 55 questions survey encompassing nine domains relevant to CeD care (awareness, gluten-free [GF] foods availability/cost/quality, GF labeling, CeD dietician availability, insurance for CeD patients, medical training, research funding, patient support groups, and unmet needs) was generated and sent to CeD experts worldwide electronically.