Publications by authors named "D S Pradeep"

Article Synopsis
  • - Osteoblastoma is a rare and benign bone tumor mainly found in the spine but can also appear in the mandible, as seen in a case involving a 38-year-old female with mild pain and swelling.
  • - Diagnosis was confirmed through clinical, radiographic, and histopathological evaluations, leading to a conservative surgical excision with no recurrence during follow-up.
  • - The report highlights the need to differentiate osteoblastoma from similar lesions like low-grade osteosarcoma and osteoid osteoma for proper treatment and better outcomes.
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Extracellular vesicles (EVs) serve as crucial mediators of cell-to-cell communication in normal physiology as well as in diseased states; they have been largely studied in regard to their role in cancer progression. However, the mechanisms by which their biogenesis and secretion are regulated by metabolic or endocrine factors remain unknown. Here, we delineate a mechanism by which EV secretion is regulated by a cholesterol metabolite, 27-hydroxycholesterol (27HC), where treatment of myeloid immune cells (RAW 264.

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Article Synopsis
  • Glomerulocystic kidney disease (GCKD) is a rare type of kidney disease characterized by cyst formation in the kidneys.
  • A case study involves a four-week-old baby girl whose prenatal ultrasound indicated severe low amniotic fluid levels, leading to further evaluation after birth.
  • Post-natal examinations showed small cysts in her kidneys, and a biopsy indicated signs of GCKD, but genetic testing did not identify any harmful variants.
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Background: Following the loss of a tooth, the new edentulous area of the ridge will undergo several adaptive modifications due to changes in function within and surrounding the socket. This bone resorption explains the need for socket preservation techniques in areas of esthetic concerns and functional demands. Demineralized freeze-dried bone allograft (DFDBA) possesses greater osteoinductive potential due to the exposure of bone morphogenetic protein (BMP-3​​​​​​)​and collagen fibrils and can be used efficiently in socket preservation techniques.

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Introduction: Colorectal cancers are the world's third most commonly diagnosed type of cancer. Currently, there are several diagnostic and treatment options to combat it. However, a delay in detection of the disease is life-threatening.

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