Background: The existing data on the morphological substrate of out-of-hospital sudden death due to ischemic (coronary) heart disease (IHD) and its relationship to other acute coronary syndromes are not sufficient and even controversial.
Material And Methods: We analyzed clinical and pathological data from 170 men who died suddenly (within 6 h) of IHD out of hospital, as well as 54 men who died in hospital a documented acute myocardial infarction (AMI).
Results And Conclusions: Majority (92,9%) of out-of-hospital sudden coronary deaths were due to AMI and 7,1%t - due to disseminated myocardial micronecroses.
A 30% increase in mean values of net weight of the heart and the weight of its individual portions in 88 males, who had suffered from coronary disease and died suddenly as a result of the first major coronary disaster (in the absence of postinfarction scars and systemic arterial hypertension) was indicative of an evenly distributed compensatory myocardial hypertrophy of the entire heart. Therefore, detection of increased heart weight may be used as an additional indicator for intravital and postmortem diagnosis of early and latent coronary heart disease.
View Article and Find Full Text PDFStudy of planimetric and weight indices of individual parts of the heart in 55 males (average age 51.2 +/- 2.7 years) who died of the first or repeated (primarily early) myocardial infarction has revealed the appearance (prior to the first major coronary event) of compensatory myocardial hypertrophy of all parts of the heart.
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