Publications by authors named "D S Miura"
Background: Monitoring fibrosis in patients with chronic liver disease (CLD) is an important management strategy. We have already reported a novel stacked microvascular imaging (SMVI) technique and an examiner scoring evaluation method to improve fibrosis assessment accuracy and demonstrate its high sensitivity. In the present study, we analyzed the effectiveness and objectivity of SMVI in diagnosing the liver fibrosis stage based on artificial intelligence (AI).
View Article and Find Full Text PDFMetabolic mechanism of lignin-derived aromatics in white-rot fungi.
Appl Microbiol Biotechnol
December 2024
Article Synopsis
- White-rot fungi, like Phanerochaete chrysosporium, are essential for breaking down lignocellulosic biomass, which includes important components like cellulose, hemicellulose, and lignin, thus contributing to the carbon cycle.
- These fungi use various enzymes—such as lignin peroxidases and cytochrome P450 monooxygenases—to degrade lignin and its derivatives, though more research is needed to fully understand the metabolic pathways involved.
- The metabolic flexibility of these fungi allows them to adapt their enzyme production, specifically through the interplay of key pathways, enhancing their efficiency in degrading lignin for potential biotechnological applications.
Article Synopsis
- Knee osteoarthritis (KOA) causes joint pain and disabilities, with procedures like OWHTO and OWDTO used to relieve symptoms and delay progression, but the impact on quadriceps strength post-surgery is not well understood.
- A study of 120 knees examined quadriceps strength before and after these surgeries, finding that strength increased significantly at 12 months post-OWHTO, while improvements in OWDTO were not statistically significant.
- The study concludes that quadriceps strength improves after both procedures, especially OWHTO, and suggests further research on its relationship with recovery outcomes and rehabilitation strategies.
The SARS-CoV-2 pandemic has challenged more scientists to detect viruses and to visualize virus-containing spots for diagnosis and infection control; however, detection principles of commercially available technologies are not optimal for visualization. Here, a convenient and universal homogeneous detection platform named proximity-unlocked luminescence by sequential enzymatic reactions from antibody and antibody/aptamer (PULSERAA) is developed. This is designed so that the signal appears only when the donor and acceptor are in proximity on the viral surface.
View Article and Find Full Text PDFNew results are presented on a high-statistics measurement of Collins and Sivers asymmetries of charged hadrons produced in deep inelastic scattering of muons on a transversely polarized ^{6}LiD target. The data were taken in 2022 with the COMPASS spectrometer using the 160 GeV muon beam at CERN, statistically balancing the existing data on transversely polarized proton targets. The first results from about two-thirds of the new data have total uncertainties smaller by up to a factor of three compared to the previous deuteron measurements.
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