A complete digital approach for the functional and esthetic rehabilitation of reconstructed jaws with microvascularized bone and extraoral skin grafts: A dental technique.

The oral rehabilitation of patients with microvascularized bone and extraoral skin grafts is a clinical challenge. The integration of these procedures with digital technologies has increased the treatment accuracy, minimizing the risk associated with anatomical variations, and improving esthetic and functional outcomes. This article presents a reproducible and completely digital approach for the functional and esthetic rehabilitation of reconstructed jaws with microvascularized bone and extraoral skin grafts.

Age and Inflammation: Insights on "Age Three Ways" from Midlife in the United States Study.

Introduction: Chronological age is a particularly well-known indicator of variability in systemic inflammation. Other pertinent aspects of age (or "age proxies") - subjective or epigenetic age - may offer nuanced information about age and inflammation associations. Using the Midlife in the United States Study, we explored how chronological, subjective, and epigenetic age were associated with inflammation.

Canopy functional trait variation across Earth's tropical forests.

Tropical forest canopies are the biosphere's most concentrated atmospheric interface for carbon, water and energy. However, in most Earth System Models, the diverse and heterogeneous tropical forest biome is represented as a largely uniform ecosystem with either a singular or a small number of fixed canopy ecophysiological properties. This situation arises, in part, from a lack of understanding about how and why the functional properties of tropical forest canopies vary geographically.

Statistical shape modelling of the left ventricle for patients with HeartMate2 and HeartMate3 ventricular assist devices.

Left ventricular assist devices (LVADs) have demonstrated promising outcomes in the management of end-stage heart failure. However, the altered intraventricular flow dynamics following LVAD implantation can lead to non-physiological shear rates and stagnant or recirculating zones, which increase the risk of thrombosis around the inflow cannula. There are conflicting recommendations regarding the optimal inflow cannula design and its association with thrombosis risk, possibly due to anatomical variations among patients.

Negative affective responsivity to daily stressors in young adults: The influence of depressive symptom severity.

Background: Evidence suggests that adults with major depressive disorder appraise daily stressor events as more severe and report stronger stressor-related negative emotions than non-depressed adults. Despite the growing number of young adults (~18-25 yrs) experiencing depressive symptoms in the absence of a formal clinical diagnosis, limited studies have examined whether current depressive symptom severity influences affective responsivity to daily stressors in young men and women. We tested the hypotheses that greater depressive symptom severity would be related to greater negative stressor appraisal characteristics and greater affective responsivity to daily stressors but not to stressor exposure frequency.