Publications by authors named "D S Gaikwad"
Natural polymers are crucial for developing sustainable biomedical solutions, as their bioactivity, biocompatibility, and biodegradability make them superior alternatives to synthetic materials. The objective of the study is to develop and characterize a chemically modified bael fruit gum (BFG) and pectin hydrogel to enhance antimicrobial activity. Due to BFG's anionic nature, it was chemically modified to introduce cationic groups, facilitating cross-linking with pectin.
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- The 21st century has seen increasing variations of pathogens, leading to significant global health issues, particularly malaria and oxidative damage, which necessitate the search for effective treatments.* -
- Research is focused on the antioxidant potential of transition metal (II) complexes with tridentate Schiff base ligands, as they might enhance both anti-malarial and antioxidant activities, offering a two-fold therapeutic benefit.* -
- Investigations into various metal complexes showed that some, particularly the Hg(II) complex, exhibit strong anti-malarial properties similar to quinine, while Cu(II) and Zn(II) complexes demonstrate significant antioxidant capabilities, supported by molecular docking studies to assess their pharmacological interactions.*
Polysaccharides have drawn a lot of attention due to their potential as carriers for drugs and other bioactive chemicals. In drug delivery systems, natural macromolecules such as polysaccharides are widely utilized as polymers. This utilization extends to various polysaccharides employed in the development of nanoparticles for medicinal administration, with the goal of enhancing therapeutic efficacy while minimizing side effects.
View Article and Find Full Text PDFWith climate emergency, COVID-19, and the rise of planetary health scholarship, the binary of human and ecosystem health has been deeply challenged. The interdependence of human and nonhuman animal health is increasingly acknowledged and paving the way for new frontiers in integrative biology. The convergence of genomics in health, bioinformatics, agriculture, and artificial intelligence (AI) has ushered in a new era of possibilities and applications.
View Article and Find Full Text PDFImproper use of water resources in irrigation that contain a significant amount of salts, faulty agronomic practices such as improper fertilization, climate change etc. are gradually increasing soil salinity of arable lands across the globe. It is one of the major abiotic factors that inhibits overall plant growth through ionic imbalance, osmotic stress, oxidative stress, and reduced nutrient uptake.
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