Publications by authors named "D S De Lorenzo"
Article Synopsis
- A study was conducted on patients who had surgery for high-risk intraductal papillary mucinous neoplasms (IPMNs) that included a mural module, focusing on the relationship between dysplasia grade and the mural module location.
- The research involved 82 patients, revealing that nearly half had high-grade dysplasia or invasive carcinoma away from the mural module, indicating that local treatment might not be safe or effective.
- The results suggest that pancreatectomy (removal of part or all of the pancreas) remains the best treatment option due to the potential risks associated with localized treatments.
Background And Objectives: Chronic knee pain, including postarthroplasty knee pain, is a major cause of morbidity. Radiofrequency ablation of genicular nerve branches is a treatment option. The literature to date has demonstrated and recommended consistent rhizotomy targets in the coronal and axial position of the three primary genicular nerve branches (superomedial genicular nerve, superolateral genicular nerve, inferomedial genicular nerve).
View Article and Find Full Text PDFUveal melanoma (UM) is the most common primary malignant intraocular tumor in adults. Distant metastasis is common, affecting around 50% of patients. Prognostic accuracy relies on molecular characterization of tumor tissue.
View Article and Find Full Text PDFUM is an aggressive intraocular tumor characterized by high plasticity and a propensity to metastasize in the liver. However, the underlying mechanisms governing liver tropism remain poorly understood. Given the emerging significance of exosomes, we sought to investigate the contribution of UM-derived exosomes to specific steps of the metastatic process.
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