Vestn Ross Akad Med Nauk
February 2016
Background: Currently all tissue engineered trachea transplants had no ciliated epithelium until transplantation, and long-term temporary lack of mucociliary clearance leads to patients' condition decline and reduced life quality in postoperative period. So, the need for a better cultivation method and studying ciliated epithelium growth characteristics in cell culture increased rapidly.
Objective: The aim of our study was to investigate cultivation offunctionally complete passaged ciliated epitheliumfor trachea tissue engineering.