Publications by authors named "D Ruttens"
Background: Patients with early stage (I-IIIA) nonsmall cell lung cancer (NSCLC) are typically treated surgery, often accompanied by (neo-)adjuvant therapy. These interventions impose a significant burden on patients and potentially impact their physical functioning (PF). The impact on PF remains uncertain and existing evidence has not yet been systematically outlined.
View Article and Find Full Text PDFChronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide and greatly reduces the quality of life. Utilizing remote monitoring has been shown to improve quality of life and reduce exacerbations, but remains an ongoing area of research. We introduce a novel method for estimating changes in ease of breathing for COPD patients, using obstructed breathing data collected via wearables.
View Article and Find Full Text PDFArticle Synopsis
- Pulmonary arterial hypertension (PAH) is a serious, rare illness that affects blood vessels in the lungs and can lead to heart failure and even death.
- Current treatments work on three main areas but don't cure the disease, so researchers are looking for new options.
- Sotatercept is a new medication that helps improve patients' health and quality of life, and it's been shown to be safe, though it can cause some side effects.
Article Synopsis
- - The study explores the effects of different exercise training methods—high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT)—on extra-pulmonary symptoms of chronic obstructive pulmonary disease (COPD), as well as their impact on cognitive and muscle function compared to healthy controls.
- - Conducted as a multi-center, randomized controlled trial, the research involves two phases: the first examines the immediate effects of a 12-week HIIT vs. MICT regimen, while the second phase tracks the long-term impact on cognitive decline and inflammation over 24 months.
- - Key outcomes include improvements in cognitive function, cardiorespiratory fitness, and muscle strength, with additional assessments of neuroinflammation