Publications by authors named "D Runowski"
Article Synopsis
- IgA nephropathy (IgAN) is a serious kidney disease linked to IgA buildup, and a large study identified 30 genetic risk factors associated with it.
- Fourteen new loci were discovered that suggest a connection between genetic influences and abnormal IgA levels.
- The research highlights inflammation-related pathways and potential drug targets, revealing that higher genetic risk scores are tied to earlier kidney failure.
Background: This study aimed to evaluate outcome of children on chronic peritoneal dialysis (PD) with a concurrent colostomy.
Methods: Patients were identified through the International Pediatric Peritoneal Dialysis Network (IPPN) registry. Matched controls were randomly selected from the registry.
Objective: There are no specific recommendations for therapeutic plasma exchange (TPE) in children after renal transplantation. The purpose of this study was to report the experience with TPE in a pediatric transplant setting.
Materials And Methods: 59 patients (mean age 12.
Article Synopsis
- The study evaluated the effectiveness of basic bladder training (BBA) in treating previously untreated children with primary monosymptomatic nocturnal enuresis (MNE), highlighting the ongoing debate about its efficacy.
- A total of 49 children participated, and results showed a significant reduction in wet nights only after three months, with BBA proving fully successful in 18% of cases by the end of the study.
- Despite confirming the limited effectiveness of BBA, the study's findings suggest a gradual improvement in response rates, although the lack of randomization is noted as a limitation.
Background: Lowe syndrome (LS) and Dent-2 disease (DD2) are disorders associated with mutations in the OCRL gene and characterized by progressive chronic kidney disease (CKD). Here, we aimed to investigate the long-term renal outcome and identify potential determinants of CKD and its progression in children with these tubulopathies.
Methods: Retrospective analyses were conducted of clinical and genetic data in a cohort of 106 boys (LS: 88 and DD2: 18).