Publications by authors named "D Ruiz-Sobremazas"

Impulsive and compulsive behaviors are associated with inhibitory control deficits. Diet plays a pivotal role in normal development, impacting both physiology and behavior. However, the specific effects of a high-fat diet (HFD) on inhibitory control have not received adequate attention.

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Article Synopsis
  • The study focuses on Fmr1-knockout (KO) rats, which are used as a model for Fragile X Syndrome and autism spectrum disorder (ASD).
  • Researchers examined the effects of chlorpyrifos (CPF), a pesticide linked to ASD, on both KO and wild-type rats by assessing metabolic changes in various brain regions and gut content at different postnatal days.
  • The findings revealed specific metabolic variations in brain tissues related to genotype and CPF exposure, including alterations in key biomarkers and metabolites associated with gastrointestinal dysfunction, while gene expression changes were minimal.
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This review highlights the significant impact of air quality, specifically particulate matter (PM), on cognitive decline and age-related diseases in the elderly. Despite established links to other pathologies, such as respiratory and cardiovascular illnesses, there is a pressing need for increased attention to the association between air pollution and cognitive aging, given the rising prevalence of neurocognitive disorders. PM sources are from diverse origins, including industrial activities and combustion engines, categorized into PM, PM, and ultrafine PM (UFPM), and emphasized health risks from both outdoor and indoor exposure.

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Air pollution has been associated with a wide range of health issues, particularly regarding cardio-respiratory diseases. Increasing evidence suggests a potential link between gestational exposure to environmental pollutants and neurodevelopmental disorders such as autism spectrum disorder. The respiratory pathway is the most commonly used exposure model regarding PM due to valid and logical reasons.

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