Publications by authors named "D Rotondi"
Introduction: The availability of epidemiological data relating to the therapy with somatropin (recombinant Growth Hormone, rGH) is scarce and mostly limited to specific clinical conditions. In Italy, the National Register of rGH users (Registro nazionale degli assuntori dell'ormone della crescita - Rnaoc) has been established since 2004 as recommended by the Italian medicine agency (Aifa). However, prevalence (P) and incidence (I) estimates in the Italian population are lacking.
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- In 2005, Italy launched a voluntary iodine prophylaxis program to improve iodine levels, but recent data on its efficacy was lacking.
- A nationwide survey conducted from 2015 to 2019 observed that 71.5% of adults and 78% of school canteens used iodized salt, with schoolchildren showing adequate urinary iodine but higher rates of neonatal TSH levels than recommended by the WHO.
- Despite achieving overall iodine sufficiency, concerns about iodine status for pregnant women persist, alongside a noted decrease in new hyperthyroidism cases.
Background: In adult population, Growth Hormone Deficiency (GHD) is a complex clinical condition with heterogeneity of causes and duration. Growth Hormone (GH) replacement therapy has beneficial effects entailing a chronic and expensive use. Therefore, entity, appropriateness and standardization of GHD treatment need to be accurately analysed.
View Article and Find Full Text PDFThe frequency of overweight (OW) and obese (OB) children has increased worldwide, particularly in economically developed countries. No studies have been conducted to verify whether the increasing frequency of OW and obesity in schoolchildren may affect the evaluation of iodine nutritional status in populations. The aim of this study was to verify whether urinary iodine concentration (UIC), thyroid volume (TV), and thyroid hypoechoic pattern may be affected by body mass index (BMI) in schoolchildren.
View Article and Find Full Text PDFContext: Analysis of a 2-screen program for congenital hypothyroidism (CH) was performed using differential dried-blood spot thyrotropin (bTSH) cutoffs of 10 mU/L at first screening (all infants) and 5 mU/L at second screening (selected infants).
Objectives: This work aimed to characterize CH infants identified by the second screening and compare infants with bTSH of 5.0 to 9.