Publications by authors named "D Rossi Sebastiano"
Musicogenic epilepsy (ME) is characterized by seizures triggered by music. The epileptogenic focus in this rare reflex epilepsy is often in the temporal lobe, although the precise localization is still unclear. A correlation between ME and the presence of GAD65 antibodies indicates a potential immunological pathogenic mechanism.
View Article and Find Full Text PDFAim: When studying brain networks in patients with Disorders of Consciousness (DoC), it is important to evaluate the structural integrity of networks in addition to their functional activity. Here, we investigated whether structural MRI, together with clinical variables, can be useful for diagnostic purposes and whether a quantitative analysis is feasible in a group of chronic DoC patients.
Methods: We studied 109 chronic patients with DoC and emerged from DoC with structural MRI: 65 in vegetative state/unresponsive wakefulness state (VS/UWS), 34 in minimally conscious state (MCS), and 10 with severe disability.
Article Synopsis
- - The study reports the case of the first Italian child diagnosed with hypomyelinating leukodystrophy (HLD), presenting symptoms such as nystagmus and movement disorders shortly after birth, alongside frequent focal seizures that were challenging to control.
- - Diagnostic methods included neurophysiologic assessments, brain MRI, and whole-exome sequencing, which revealed a specific genetic variant associated with the condition.
- - The findings suggest that early signs of HLD can include hyperkinetic movement disorders and seizures, highlighting the need for genetic screening in infants showing such symptoms to ensure timely diagnosis and intervention.
Article Synopsis
- Current research shows that different brain areas process visual recognition of objects and the understanding of their names, but the idea of embodiment suggests these processes may share neural mechanisms.
- A study using behavioral tests and MEG (magnetoencephalography) examined how our brains respond to graspable objects and tools when they are shown visually or presented as words.
- The results indicate that both the recognition of an object and its verbal label activate similar brain processes, reinforcing the idea that our understanding of objects is closely tied to how we physically interact with them.
Background: GENetics of mOyaMoyA (GEN-O-MA) project is a multicenter observational study implemented in Italy aimed at creating a network of centers involved in moyamoya angiopathy (MA) care and research and at collecting a large series and bio-repository of MA patients, finally aimed at describing the disease phenotype and clinical course as well as at identifying biological or cellular markers for disease progression. The present paper resumes the most important study methodological issues and preliminary results.
Methods: Nineteen centers are participating to the study.