Publications by authors named "D Rosenman"
LIDAR (from "light detection and ranging" or "laser imaging, detection, and ranging") is an evolving three-dimensional scanning technology with historical applications in various fields. However, the applicability of LIDAR in the field of medicine has mostly not been examined thus far. Here, we review the basic principles governing LIDAR and its potential to be used in three notable use cases in the context of remote patient monitoring: geriatric fall prevention, postoperative recovery monitoring, and home safety assessment.
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- High pressure NMR was used to study Aβ42 and Aβ40 protein variants with mutations linked to Alzheimer’s disease, specifically E22G and D23N.
- At normal pressure, only minor changes were detected in the chemical shifts of the proteins, but high pressure NMR revealed significant sensitivity at the Q15, K16, and L17 positions across all variants.
- The findings indicate that this pressure-sensitive area is associated with increased β-sheet structure and faster protein aggregation, which are important factors in Alzheimer's disease progression.