Publications by authors named "D Rosati"

Vulvovaginal candidiasis (VVC) is one of the most common infections caused by . VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated with colonization of the vaginal mucosa. Compared to other host niches in which can cause infection, the vaginal environment is extremely rich in lactic acid that is produced by the vaginal microbiota.

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: Non-Small Cell Lung Cancer (NSCLC) remains a challenging disease to manage with effectiveness. Early detection and precise monitoring are crucial for improving patient outcomes. Circulating tumor DNA (ctDNA) offers a non-invasive cancer detection and monitoring method.

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: The advantage of a robotic-assisted (RARP) over a laparoscopic (LRP) approach in radical prostatectomy (RP) remains to be demonstrated. : The aim of the study is to use a homogeneous population in real life and single primary surgeon surgery to analyze the oncological and functional results based on the type of surgical approach and pathological features. : This is a prospective trial on non-metastatic prostate cancer (PCa) patients considered after a multidisciplinary decision to conduct a RP, using a RARP or LRP approach.

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Article Synopsis
  • - Vulvovaginal candidiasis (VVC) impacts up to 75% of women, with roughly 8% experiencing frequent recurrent cases (RVVC), due to host response issues and excessive inflammation.
  • - The study examined inflammatory protein levels in 158 RVVC patients and 92 healthy women, using advanced technology to analyze 92 different proteins, without finding significant links to hormonal contraceptive use.
  • - RVVC patients showed lower levels of Fibroblast Growth Factor 21 (FGF-21), a potential marker for immune issues related to RVVC, highlighting the possibility of developing new diagnostic tools and treatments.
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Lung cancer (LC) continues to be an important public health problem, being the most common form of cancer and a major cause of cancer deaths worldwide. Despite the great bulk of research to identify genetic susceptibility genes by genome-wide association studies, only few loci associated to nicotine dependence have been consistently replicated. Our previously published study in few phenotypically discordant sib-pairs identified a combination of germline truncating mutations in known cancer susceptibility genes in never-smoker early-onset LC patients, which does not present in their healthy sib.

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