Publications by authors named "D Rolland"
Article Synopsis
- RUNX1 is crucial for human blood formation and is linked to various mutations, particularly in acute myeloid leukemia (AML), leading the WHO to create a category for mutations in RUNX1 in 2016.
- A recent study examined 32 AML patients at Strasbourg University Hospital to explore features related to RUNX1 mutations and the presence of plasmacytoid dendritic cells (pDC).
- The findings indicated that AML cases with RUNX1 mutations don't show consistent characteristics and are not a separate AML subtype, with some fitting the criteria for a recently recognized pDC-related AML according to the 2022 WHO classification.
Introduction: It is recommended to use two chronometric assays of different principles for the diagnosis of lupus anticoagulant (LA), consisting in diluted Russell Viper Venom Time (dRVVT) and activated Partial Thromboplastin Time (aPTT). Yet, there are only a few integrated aPTT assays; this study aims to evaluate one of them: Cephen LS/Cephen (Hyphen Biomed).
Method: 249 samples of patients were included in this study.
Article Synopsis
- A one-health approach suggests new insights into the transmission of pathogenic bacteria responsible for serious infections in humans, which primarily originate from food animals.
- Research analyzing over 3,100 samples reveals that approximately 8% of extraintestinal infections, mainly urinary tract infections, are linked to foodborne zoonotic strains, which show similar disease severity as non-foodborne strains.
- Specific lineages of these foodborne strains, ST131-22 and ST58, display high virulence, and this study's methods could help identify and mitigate risks from these strains in future public health efforts.