Publications by authors named "D Roberge"

Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), representing the majority of all lymphomas arising in the skin. The disease treatment focuses on managing symptoms and preventing disease evolution. To date, there is no gold standard for MF-CTCL treatment.

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Introduction: This study develops two new multi-institutional hippocampal-sparing whole-brain RapidPlan™ models (HLS-EC-WB and HMS-EC-WB) inspired by CCTG-CE.7 featuring enhanced target coverage with varying hippocampal sparing (limited and moderate).

Methods: New dosimetric scorecards were created to quantify the models' clinical intent.

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  • Pancreatic cancer has limited treatment options, and a new method called Alpha DaRT, using alpha-particle radiation therapy, is being tested to improve outcomes.
  • A study evaluated the safety and feasibility of using EUS-guided Alpha DaRT to treat patients with advanced, inoperable pancreatic cancer, with procedures conducted successfully between March and September 2023.
  • Results showed that while some adverse events occurred, most were related to disease progression rather than the treatment, and preliminary findings indicate that this approach is both feasible and safe, warranting further investigation.
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  • The study aimed to track the outcomes of patients with brain arteriovenous malformations (AVMs) who were managed conservatively, revealing key statistics on related morbidity and mortality over a 10-year period.
  • Out of 1010 patients initially recruited, 434 were analyzed, with a majority having unruptured low-grade AVMs, demonstrating a 5% occurrence of serious outcomes and a higher risk in those with a history of rupture or older age.
  • During the follow-up of approximately 3.2 years, 8% of patients experienced major intracranial hemorrhages, highlighting the ongoing risks associated with conservative management of AVMs.
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  • This study looked at whether radiotherapy could help reduce pain from liver cancer in patients who weren't getting better with regular treatments.
  • It included 66 patients who were given either radiotherapy and extra care or just extra care alone.
  • The researchers wanted to see if the patients felt less pain after a month and found out if the treatment was safe for them.
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