Open globe injuries: Epidemiology, visual and surgical predictive variables, prognostic models, and economic cost analysis.

Background: Open globe injuries (OGI) represent a visually and economically devastating cause of vision loss. We examined the epidemiology, predictive variables, prognostic models, and economic cost of surgically managed OGI.

Methods: A retrospective tertiary centre study from 2008 to 2018 of 155 consecutive OGI in individuals aged 16 and older was performed.

Microbial Keratitis and Ocular Surface Disease: A 5-Year Study of the Microbiology, Risk Factors and Clinical Outcomes in Sydney, Australia.

: To report the microbiological and clinical profiles, and outcomes of patients with microbial keratitis who had ocular surface disease (OSD) at the Sydney Eye Hospital, Australia over a 5-year period.: A retrospective case-series study was conducted. Patients diagnosed with microbial keratitis who had a history of OSD (dry eye, blepharitis, Steven Johnson syndrome (SJS) and ocular cicatricial pemphigoid (OCP)) from 1 January 2012 to 31 December 2016 were identified from hospital coding and pathology data.

Clinical translation of recommendations from randomized trials for management of herpes simplex virus keratitis.

Importance: To standardize initial anti-viral therapy for herpes simplex keratitis (HSK).

Background: To determine prescribing trends for the management of HSK and compare the trends to available clinical trial evidence.

Design: Retrospective review of patients at the Sydney Eye Hospital, Australia.

Corneal biopsy for diagnosis of recalcitrant microbial keratitis.

Purpose: To document the findings of corneal biopsies for progressive microbial keratitis in a large tertiary referral institution.

Methods: A retrospective medical records review of all patients who underwent at least one corneal biopsy for the diagnosis of microbial keratitis at Sydney Eye Hospital, Australia between January 1, 2010 and December 31, 2016 was performed.

Results: Thirty-eight patients (18 men and 20 women) underwent a corneal biopsy for progressive microbial keratitis unresponsive to broad-spectrum topical antimicrobials.