Pediatric trauma and resuscitation: optimizing care in an evolving landscape.

Purpose Of Review: Penetrating firearm-related injury has increased mortality rates in children in the USA. This article summarizes trends in pediatric injury patterns, the unique coagulation system of infants, and key components of hemostatic resuscitation in children.

Recent Findings: Firearm-associated penetrating trauma increased mortality and led to higher rates of pediatric massive transfusions.

Acetic acid-induced stress granules function as scaffolding complexes for Hog1 activation by Pbs2.

Stress-activated protein kinases (SAPKs) respond to a wide variety of stressors. In most cases, the pathways through which specific stress signals are transmitted to the SAPK are not known. We show that the yeast SAPK Hog1 is activated by acetic acid through an intracellular mechanism that does not involve stimulation of the high osmolarity glycerol (HOG) signaling pathway beyond its basal level.

Multiethnic prevalence of the G1 and G2 variants among the Israeli dialysis population.

Background And Hypothesis: The two apolipoprotein L1 () variants, G1 and G2, are common in populations of sub-Saharan African ancestry. Individuals with two of these alleles (G1 or G2) have an increased risk for a spectrum of non-diabetic chronic kidney diseases. However, these variants are typically not observed outside of populations that self-identify as current continental Africans or having clear recent African ancestry such as, most notably, African Americans, and other large population groups in the Americas and several European countries.

Navigating the controversy: Public perspectives on free-roaming cat populations and control strategies in Israel.

The debate surrounding the management of free-roaming cat populations is multifaceted, with conflicting views between conservationists and cat advocates. In Israel, which is characterized by densely populated free-roaming cat communities, cat numbers remain high despite extensive Trap-Neuter-Return (TNR) efforts. Recognizing the importance of public engagement for ensuring success of control campaigns, we aimed to gather public opinion on the free-roaming cat phenomenon and control strategies.

Pediatric head and neck sarcomas: a retrospective study from a national tertiary referral center.

Unlabelled: This study aims to analyze the demographics, therapeutic approaches, and outcomes of pediatric sarcomas of the head and neck treated at a single tertiary referral center. We retrospectively reviewed the medical charts of all pediatric patients diagnosed with head and neck sarcomas treated at the Tel Aviv Sourasky Medical Center during 2002-2021. Clinical data, oncologic and surgical treatments, and outcome measures were retrieved from electronic medical files.