Publications by authors named "D Ricci"
Background: The goal of this FDA-committed, post authorization study was to assess the real-world effectiveness of Ad26.COV2.S in preventing observed COVID-19 disease in individuals in the United States interacting with the healthcare system who were vaccinated according to the national immunization recommendations.
View Article and Find Full Text PDFPurpose: This cross-sectional monocentric study aims to utilize the Early Childhood Attention Battery to investigate early attention patterns in young preterm children and ascertain the extent to which their attentional abilities diverge from those of term peers.
Methods: Inclusion criteria encompassed gestational age < 34 weeks, with assessments conducted between 3 and 5 years 11 months. Exclusion criteria included major brain lesions, significant motor or behavioral disorders, and intellectual functioning with IQ < 70.
Article Synopsis
- Nonsense mutations lead to a stop signal in protein production, resulting in non-functional proteins and contributing to diseases like cystic fibrosis (CF).
- This research explores the potential of NV848, a drug designed to promote the continuation of protein synthesis, to enhance CFTR protein expression in a mouse model with a specific CF-causing mutation.
- The study evaluates the drug's stability, distribution in the body, and effectiveness in restoring CFTR protein in mice, suggesting NV848 could be a valuable treatment for CF patients with nonsense mutations.
Article Synopsis
- Bacterial evolution is heavily influenced by horizontal gene transfer (HGT), which helps map community interactions but doesn't facilitate control over these interactions for engineered strains.
- Toxin-antitoxin (TA) systems are common agents of selection in bacteria, yet their effectiveness is hindered by inconsistent distribution among host bacteria.
- The study identifies unique TA signatures within HGT communities, linked to plasmid competition, and proposes that these signatures can aid in understanding and manipulating the interactions between plasmids, hosts, and phage within bacterial communities.