Publications by authors named "D Ribe"
Intelligent data analysis to model and understand live cell time-lapse sequences.
Methods Inf Med
January 2013
Background: One important aspect of cellular function, which is at the basis of tissue homeostasis, is the delivery of proteins to their correct destinations. Significant advances in live cell microscopy have allowed tracking of these pathways by following the dynamics of fluorescently labelled proteins in living cells.
Objectives: This paper explores intelligent data analysis techniques to model the dynamic behavior of proteins in living cells as well as to classify different experimental conditions.
Article Synopsis
- Idiopathic fibrosing pancreatitis is linked to autoimmune diseases like Sjögren's syndrome and ulcerative colitis, often developing in younger individuals.
- A case involving a 25-year-old man highlighted symptoms such as epigastric pain and jaundice, with imaging revealing severe changes in the pancreas and bile ducts.
- Surgical intervention was successful in this case, indicating that early consideration of idiopathic fibrosing pancreatitis is important in young patients with jaundice, with glucocorticoids as the first treatment option.
Cardiac tissues express constitutively an NADPH oxidase, which generates reactive oxygen species (ROS) and is involved in redox signaling. Myocardial metabolism generates abundant adenosine, which binds to its receptors and plays important roles in cardiac function. The adenosine A2A receptor (A2AR) has been found to be expressed in cardiac myocytes and coronary endothelial cells.
View Article and Find Full Text PDFThe translocation of glucose transporter-4 (GLUT4) to the cell surface is a complex multistep process that involves movement of GLUT4 vesicles from a reservoir compartment, and docking and fusion of the vesicles with the plasma membrane. It has recently been proposed that a p38 mitogen-activated protein kinase (MAPK)-dependent step may lead to intrinsic activation of the transporters exposed at the cell surface. In contrast to data obtained in muscle and adipocyte cell lines, we found that no insulin activation of p38 MAPK occurred in rat adipose cells.
View Article and Find Full Text PDF[Thiotepa eyedrops for prevention of pterygium recurrence: 18 years of use].
J Fr Ophtalmol
March 1999
Purpose: To analyze effectiveness and side effects of thiotepa eyedrops utilized to prevent postoperative pterygium recurrence, with a retrospective study allowing a long follow-up.
Methods: This work deals with 64 cases of pterygium, among them 8 were recurrent. Only growing or very important pterygiums were operated on (14 cases were reaching the pupillary area).