Publications by authors named "D Rex"

Isolated ischemic necrosis of the cecum (INC) is an uncommon benign condition that occurs most often in elderly patients. The clinical presentation and radiographic findings often mimic acute appendicitis or malignancy. This study aimed to investigate the clinicopathologic features of mass-forming INC.

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Article Synopsis
  • - Colonoscopy is the most commonly used screening test for colorectal cancer in the U.S., with high sensitivity for detecting precancerous lesions, allowing screenings every 10 years, and possibly every 15 years for those with normal results.
  • - There is substantial evidence showing colonoscopy reduces colorectal cancer incidence and mortality, supported by various studies, including comparisons with other screening methods like flexible sigmoidoscopy.
  • - Advances in colonoscopy techniques, such as improved mucosal exposure methods and non-device strategies, have enhanced detection rates of precancerous lesions, along with safer resection techniques for small lesions, increasing the effectiveness of this screening option.
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Background And Aims: In the colorectum, intramucosal carcinoma (IMC), like high-grade dysplasia (HGD), should be resected endoscopically. We were interested to understand how real-world treatment of IMC cases compares to management of HGD and T1 colorectal cancer (CRC).

Methods: A multicenter cohort study was conducted.

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Article Synopsis
  • New image enhancement techniques and improved endoscopic quality haven't increased the routine use of the resect-and-discard approach for small polyps, even though endoscopists can achieve the necessary quality to perform optical diagnoses.
  • Recent advancements in Artificial Intelligence, specifically Computer Assisted Characterisation (CADx), show promise for better diagnosing diminutive polyps and potentially enhancing the adoption of resect-and-discard strategies.
  • While pathology diagnosis faces challenges like errors and variability, new AI-driven paradigms are emerging, but further research and real-world implementation studies are needed to boost acceptance and address liability concerns among endoscopists.
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