An affordable, handheld multimodal microscopic system with onboard cell morphology and counting features on a mobile device.

Microscopes, bright-field (BF) and fluorescence microscopes, in particular, are ubiquitous for clinical diagnostics, cellular and microbiological investigations and in research laboratories. However, the size, cost, fragility and need for skilled personnel to operate these tools restrict their use in resource-limited settings. As an alternative platform, herein, we report a flexible multimodal imaging system that operates in BF and fluorescence modes using a smartphone.

Molecular characterization of O1 strains circulating in Assam: a north eastern state of India.

Background And Objectives: Information on the genetic epidemiology of cholera in Assam, a northeastern state of India is lacking despite cholera being a major public health problem. The study aimed to determine the virulence genes and genes encoding antibiotic resistance in isolates and to determine the prevalent genotypes based on the presence or absence of the virulence genes and genotype.

Materials And Methods: Twenty-five strains were subjected to conventional biotyping and serotyping followed by multiplex PCR to detect and and antibiotic resistance genes.

Co-circulation of different genotype, sub-genotype and serotypes of hepatitis B virus (HBV) and its epidemiology in Assam: A north-eastern state of India.

Purpose: Hepatitis B virus (HBV) infection is a global health problem. HBV has different genotypes and subgenotypes with geographical distinctiveness.

Aims: To study the molecular epidemiology and distribution pattern of HBV in Assam; a distinct state of India that may have different genotypic divergence.

Molecular typing of dengue viruses circulating in Assam, India during 2016-2017.

Background & Objectives: The global incidence of dengue has grown dramatically in recent decades and Assam, India has witnessed several outbreaks of dengue since 2015. Although during post-monsoon months (September to December), most cases of dengue in Assam are recorded but incidence of dengue in Assam has been slowly changing from being endemic to being hyper endemic. Therefore, this study was carried out to determine the serotypes and genotypes of dengue virus prevalent in Assam during the period of 2016-2017.

Design of a 3D printed smartphone microscopic system with enhanced imaging ability for biomedical applications.

Portable, low-cost smartphone platform microscopic systems have emerged as a potential tool for imaging of various micron and submicron scale particles in recent years (Ozcan; Pirnstill and Coté; Breslauer et al.; Zhu et al.).