Publications by authors named "D RADULESCU"

Chronic inflammation and psychosocial factors significantly influence cancer progression and patient behavior in seeking medical care. Understanding their interplay is essential for enhancing early detection and developing personalized treatment strategies. This study aims to develop a comprehensive patient profiling model by comparing non-melanoma skin cancer (NMSC) and colorectal cancer (CRC).

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Orthopedic screws are subjected to high mechanical stress, corrosive environment, and microbial colonization, which may cumulatively lead to implant failure and periprosthetic joint infections. To overcome these issues, this study has focused on modifying the surface chemistry and topography of screws utilized in knee intervention toward enhancing their mechanical and biological behaviors. Specifically, this study has explored the optimization of composite coatings made of polycaprolactone (PCL), graphene oxide (GO), and Meropenem (MRP) via the matrix-assisted pulsed laser evaporation (MAPLE) technique.

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Background: This study examines the impact of the COVID-19 pandemic on abdominal trauma management by comparing pre-pandemic (17 February 2018-26 February 2020) and pandemic periods (27 February 2020-7 March 2022).

Methods: Analyzing data from 118 patients at the Emergency County Clinical Hospital of Craiova, we identified significant shifts in clinical practices affecting patient outcomes.

Results: During the pandemic, a moderate increase in surgical interventions for specific abdominal traumas indicated the effective adaptation of the medical system.

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Article Synopsis
  • The study aimed to classify knee osteoarthritis (KOA) patients by their phenotypes and assess their functional status using the International Classification of Functioning.
  • Conducted at Filantropia Hospital from June 2022 to November 2023, it involved 100 patients categorized into five phenotypes based on pain and underlying health conditions.
  • Results showed significant improvements in phenotypes with comorbidities, highlighting reductions in pain and enhancements in mobility and daily activities, ultimately improving patients' quality of life.
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Article Synopsis
  • - The article explores how infections may contribute to cardiovascular diseases (like atherosclerosis and strokes) and neurological disorders (such as Alzheimer's and Parkinson's) through mechanisms like inflammation and immune responses.
  • - Evidence suggests that systemic inflammation from infections can worsen cardiovascular conditions and may play a role in the development of neurological diseases, indicating a potential link between these health issues and bacterial presence.
  • - Further research is necessary to understand these connections better and develop targeted therapies that combine infection eradication with anti-inflammatory treatments to improve patient outcomes.
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