Publications by authors named "D R Taaffe"

Purpose: Breast cancer treatments often lead to unfavourable changes in body composition, physical fitness, and quality of life (QoL). We compared the effects of resistance training (RT) and high-intensity interval training (HIIT) on these outcomes in survivors of breast cancer.

Methods: Twenty-eight survivors of breast cancer, post-treatment (Stage I-III), aged 55.

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Background And Objective: An array of treatment-related toxicities result from androgen deprivation therapy (ADT) in patients with prostate cancer (PCa), compromising function and health-related quality of life (HRQoL). Exercise has been demonstrated to counter a number of these adverse effects including decreased HRQoL; however, when exercise should be initiated is less clear. This study aims to examine whether commencing exercise when ADT is initiated rather than later during treatment is more effective in countering adverse effects on HRQoL.

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Exercise is a therapeutic approach in cancer treatment, providing several benefits. Moreover, exercise is associated with a reduced risk for developing a range of cancers and for their recurrence, as well as with improving survival, even though the underlying mechanisms remain unclear. Preclinical and clinical evidence shows that the acute effects of a single exercise session can suppress the growth of various cancer cell lines in vitro.

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Article Synopsis
  • - The study aimed to investigate whether adding creatine supplementation to resistance exercise could offer more benefits for men with prostate cancer undergoing androgen deprivation therapy (ADT) than resistance exercise alone, particularly in terms of lean mass, strength, and physical function.
  • - Conducted over 12 weeks with 30 participants, the trial compared two groups: one performing resistance exercise with a placebo and the other with creatine, both achieving significant improvements in lean mass, muscle strength, and physical function.
  • - The results showed that while both groups experienced similar improvements in the measured outcomes, there were no significant differences between the groups, suggesting that creatine supplementation doesn't provide additional benefits over resistance exercise alone.
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Cognitive function is improved acutely after aerobic and/or resistance exercise, but it is unclear if the types of muscle contraction can influence this effect. This study tested the hypothesis that undertaking an acute bout of exercise with eccentric than concentric contractions would be more beneficial for improving cognitive function post-exercise in older adults. Twenty healthy older adults (66-75 years) performed descending stair walking (DSW), ascending stair walking (ASW), and resistance exercise of the knee extensors with eccentric-only (RE-ECC) or concentric-only contractions (RE-CON) for ∼20 min each with a week between exercises in a randomized order.

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