Publications by authors named "D R Spahn"
Background: Iron deficiency anemia in the perioperative setting is treated predominantly with intravenous iron formulation, of which ferric carboxymaltose may induce hypophosphatemia by modulating fibroblast growth factor 23.
Methods: In this single-center, prospective, randomized, double-blind trial, we consented 92 adult patients scheduled for elective major abdominal or thoracic surgery. These patients either had isolated iron deficiency (plasma ferritin <100 ng/mL or transferrin saturation < 20 %) or iron deficiency anemia (hemoglobin (Hb) 100-130 g/L with plasma ferritin <100 ng/mL or transferrin saturation < 20 %).
Article Synopsis
- The study looked at how much blood patients lost during surgery if they had high levels of certain blood thinners called FXa inhibitors, without reversing their effects before surgery.
- Researchers collected data from 32 patients who had emergency operations between 2018 and 2022 and found that blood loss was generally low, even with high levels of the medicine in their systems.
- The results showed that one type of blood thinner caused a bit more blood loss than another, but overall, the method of waiting and monitoring worked fine, and no serious complications happened.
Background: Training schoolchildren in basic life support ('Kids-Save-Lives' training) is widely believed to improve outcomes from out-of-hospital cardiac arrest. Numerous programmes have been launched, but to our knowledge, neither children nor schoolteachers have been directly involved in designing these courses. This is unfortunate, as it is well-known that children (as the target goup of training) learn differently from adults.
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