Laboratory models that help us understand the neural mechanisms associated with how stress, particularly interpersonal stress, affects children's and adolescents' emotions are paramount but are limited if that understanding lacks validity in adolescents' daily lives. There is a lack of research that addresses the ecological validity of visual stimuli to induce stress in participants while measuring participants' neural response to that stimuli. This approach is needed if we are to identify the neural mechanisms that underlie the effect of stressful events on individuals' emotional functioning.
View Article and Find Full Text PDFEnviron Pollut
October 2019
Unlabelled: Many cities fail to meet air quality standards, which results in increased risk for pulmonary disorders, including asthma. Human and experimental studies have shown that diesel exhaust (DE) particles are associated with worsening of allergic asthma. Biodiesel (BD), a cleaner fuel from renewable sources, was introduced in the eighties.
View Article and Find Full Text PDFAims: Vascular endothelial growth factor (VEGF) increases angiogenesis by stimulating endothelial cell (EC) migration. VEGF-induced nitric oxide ((•)NO) release from (•)NO synthase plays a critical role, but the proteins and signaling pathways that may be redox-regulated are poorly understood. The aim of this work was to define the role of (•)NO-mediated redox regulation of the sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) in VEGF-induced signaling and EC migration.
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