Importance: Creativity is important for problem solving, adaptation to a changing environment, and innovation. Neuroimaging studies seeking to map creativity have yielded conflicting results, and studies of patients with brain disease have reported both decreases and paradoxical increases in creativity, leaving the neural basis of creativity unclear.
Objective: To investigate the brain circuit underlying creativity and assess its association with brain injury and neurodegenerative disease.
The endosomal pathway is essential for regulating cell signaling and cellular homeostasis. Rab5 positive early endosomes receive proteins from the plasma membrane. Dependent on a ubiquitin mark on the protein, they will be either recycled or sorted into intraluminal vesicles (ILVs) by endosomal sorting complex required for transport (ESCRT) proteins.
View Article and Find Full Text PDFUnderstanding insect behaviour and its underlying drivers is vital for interpreting changes in local biodiversity and predicting future trends. Conventional insect traps are typically limited to assess the composition of local insect communities over longer time periods and provide only limited insights into the effects of abiotic factors, such as light on species activity. Achieving finer temporal resolution is labour-intensive or only possible under laboratory conditions.
View Article and Find Full Text PDFMovement performance of insects is an important measure of physiological fitness and is likely affected by novel stressors associated with global change. Reduced fitness can lead to smaller foraging areas and thus to decreasing abundance, diversity and nutritional quality, which could weaken insect populations and contribute to global insect decline. Here, we combined two different methods: An experimental semi-field design applying treatments in outdoor flight cages and a follow-up experiment conducted in the laboratory, in which different parameters of movement performance, such as (a) velocity, (b) duration and (c) distance of an insect's flight can be quantified.
View Article and Find Full Text PDFObjectives: Clinical examination alone cannot reliably rule out significant traumatic abdominal injury. Computed tomography (CT) has become the primary method for evaluating blunt abdominal trauma and clinicians rely heavily on it to rule out abdominal injury. Ultrasound examination may miss significant abdominal injury particularly in stable patients.
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