Publications by authors named "D R Mount"

Article Synopsis
  • Outdoor play is crucial for children's health and development, and ECECs can help provide this access.
  • The PRO-ECO study tested an intervention designed to increase outdoor play in children aged 2.5 to 6 years across eight ECECs in Vancouver.
  • Although the initial results showed no significant overall changes in outdoor play participation, there was a slight positive trend in the intervention group 6 months post-implementation, suggesting further research is needed to evaluate the intervention's effectiveness fully.
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Uric acid is a toxin retained with advancing kidney disease. Clinical manifestations of hyperuricemia include gout and systemic inflammation that are associated with increased risk of cardiovascular mortality. As many as one-third of all patients with chronic kidney disease have a history of gout, yet <25% of these patients are effectively treated to target serum urate levels of ≤6 mg/dl.

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Article Synopsis
  • Caffeine is a central nervous system stimulant that may lower serum urate levels and help prevent gout through its impact on urate transporters.
  • Research involving human renal cells and frog oocytes showed that caffeine inhibits urate uptake more effectively than adenosine, especially in the presence of insulin.
  • The findings suggest that caffeine's ability to inhibit specific urate transporters, particularly under high insulin conditions, could be a significant factor in its urate-lowering effects.
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