Publications by authors named "D R LeGrand"

Glycans are known to be fundamental for many cellular and physiological functions. Congenital disorders of glycosylation (CDG) currently encompassing over 160 subtypes, are characterized by glycan synthesis and/or processing defects. Despite the increasing number of CDG patients, therapeutic options remain very limited as our knowledge on glycan synthesis is fragmented.

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Copper pollution can alter biological and trophic functions. Organisms can utilise different tolerance strategies, including accumulation mechanisms (intracellular vacuoles, external chelation, etc.) to maintain themselves in copper-polluted environments.

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Context-dependent dispersal allows organisms to seek and settle in habitats improving their fitness. Despite the importance of species interactions in determining fitness, a quantitative synthesis of how they affect dispersal is lacking. We present a meta-analysis asking (i) whether the interaction experienced and/or perceived by a focal species (detrimental interaction with predators, competitors, parasites or beneficial interaction with resources, hosts, mutualists) affects its dispersal; and (ii) how the species' ecological and biological background affects the direction and strength of this interaction-dependent dispersal.

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Dispersal is a well-recognized driver of ecological and evolutionary dynamics, and simultaneously an evolving trait. Dispersal evolution has traditionally been studied in single-species metapopulations so that it remains unclear how dispersal evolves in metacommunities and metafoodwebs, which are characterized by a multitude of species interactions. Since most natural systems are both species-rich and spatially structured, this knowledge gap should be bridged.

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Article Synopsis
  • Ecological niches for species survival and reproduction are shaped by both abiotic conditions and interactions with similar (conspecifics) and different species (heterospecifics).
  • The study explores how these factors influence dispersal decisions, particularly focusing on temperature, density, and species interactions in ciliate microcosms.
  • Results showed that temperature and density influenced dispersal rates, but interactions with other species did not affect how temperature influenced dispersal, highlighting the complexities of ecological interactions in community dynamics.
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