Age Matters: Early-Onset Rectal Cancer Exhibits Higher Rates of Pathological Complete Response: A Retrospective Analysis of the Influence of Young Age on Treatment Success in Stage II-III Rectal Cancer.

Background: The incidence of rectal cancer has decreased overall, but the incidence of early-onset rectal cancer (eoRC) has increased. Early-onset rectal cancer and late-onset rectal cancer (loRC) differ due to phenotypical, genetic characteristics, and higher stage presentations in eoRC. Thus, eoRC patients undergo more aggressive neoadjuvant treatments.

Elasticity Characteristics of Thenar Muscles in Carpal Tunnel Syndrome.

Objective: Measurement of thenar muscle elasticity by ultrasound shear wave elastography (SWE) may be useful for the diagnosis and evaluation of carpal tunnel syndrome (CTS), but there is a paucity of information on SWE of the thenar muscles in patients with CTS. The purpose of this study was to investigate the elasticity of the thenar muscles in patients with CTS.

Methods: Twenty-two adult patients with a referral diagnosis of CTS (27 hands) and 20 healthy volunteers as a control (20 dominant hands) participated in this study.

Case Report: Avoiding misdiagnosis in amyloidosis-navigating transthyretin genopositivity and monoclonal gammopathy in a patient with advanced heart failure and spinal stenosis.

Background: A 63-year-old Black woman presented with progressive exertional dyspnea and chronic lower back pain. The course and findings in her case are instructive.

Case Report: Family history was notable for cardiac deaths.

Reducing the positive margins rate for anal melanoma in the modern era: a national propensity score matched study.

Anal Melanoma (AM) is a rare and aggressive disease lacking standardized treatment protocols. Despite advancements in medical oncology, the 5-year overall survival (OS) remains at 20%. Local surgery (LS) has gained popularity over radical surgery (RS) due to its comparable OS when negative margins are achieved.

Outcomes Following Direct Anterior Approach Total Hip Arthroplasty: A Contemporary Multicenter Study.

Background: The direct anterior approach (DAA) is a popular approach for primary total hip arthroplasty (THA). However, the contemporary outcomes for DAA THA need further elucidation. Therefore, we aimed to describe implant survivorship, complications, and clinical outcomes after DAA THA.