Long-term efficacy and safety of botulinum toxin A injections to treat blepharospasm and hemifacial spasm.

Background: To evaluate efficacy and safety of botulinum toxin A injections after more than 10 consecutive years of treatment for benign essential blepharospasm and hemifacial spasm.

Design: Retrospective chart review at university-affiliated hospital.

Participants: Study consisted of 64 patients treated with botulinum toxin A injections between October 2005 and May 2006.

Cicatricial entropion following docetaxel (Taxotere) therapy.

We report eyelid margin changes in 3 patients after docetaxel treatment for breast cancer. These patients were referred to Cincinnati Eye Institute for eyelash abnormalities and/or epiphora and all had been treated with docetaxel in the near past. The ophthalmic complaints started soon after chemotherapy.

Intraoperative predictability of temporal artery biopsy results.

Purpose: To determine whether inflammatory/granulomatous changes of giant cell arteritis can be grossly identified by the surgeon during temporal artery biopsy to allow institution or discontinuation of steroid therapy without delay.

Methods: The records of 113 consecutive patients operated on by the same surgeon (R.C.

Surgical management of recurrent localized eyelid amyloidosis.

Amyloidosis is a disease of unknown origin characterized by the widespread or localized deposition of amorphous hyaline material, amyloid, in various body tissues, including the ocular and orbital structures. Primary advanced localized amyloidosis involving the eyelid and conjunctiva is a rare cause of diffuse eyelid thickening. Management of these cases is often unsatisfactory because of the diffuse deposition of amyloid tissue and the increased risk of intraoperative hemorrhage, due to the fragile vessels encountered in amyloidosis.