Publications by authors named "D R Kireeva"

Article Synopsis
  • The study investigates whether people believe that maintaining cognitive capabilities is necessary for maintaining wisdom, particularly in the context of age-related cognitive decline and Alzheimer's disease (AD).
  • Most participants felt that wisdom can still exist in individuals experiencing significant cognitive declines, with common beliefs that wisdom is a stable trait, can emerge during lucid moments in severe AD, and that wisdom and cognitive abilities are separate.
  • This research highlights that many view wisdom as an unchangeable quality, suggesting a need to reassess how wisdom and cognition are understood in relation to aging and cognitive decline.
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The neurodegenerative diseases have a complex pathogenetic mechanism comprising oxidative stress and receptor system dysfunction caused by various damaging factors such as, for example, brain hypoxia. The purpose of this study was to elucidate the influence of hexahydropyrimidine derivatives on learning, memory, and orientation and locomotor activities in the passive avoidance (PA) and open field (OF) tests and to evaluate these compounds for their potential antihypoxic and antioxidant action on normobaric hypercapnic hypoxia and toxic hypoxia models. We demonstrated that compounds 1a and 1e administered as a single 100 mg/kg dose (p.

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