Publications by authors named "D R Friedland"

Article Synopsis
  • The study aimed to examine the link between cardiovascular disease (CVD) and sensorineural hearing loss (SNHL).
  • A systematic review was conducted, screening 3,440 abstracts and including 68 relevant studies from several medical databases.
  • The findings indicate that surgeries like coronary artery bypass graft (CABG) and conditions like coronary artery disease (CAD) are consistently related to SNHL, whereas other risk factors like hypertension (HTN) and hyperlipidemia (HLD) show inconsistent associations.
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Background: Benign Paroxysmal Positional Vertigo (BPPV) is a common vestibular disorder significantly impacting older adults, characterized by brief episodes of vertigo triggered by head movements. Accurate and timely diagnosis of BPPV can be challenging due to its overlapping symptoms with other conditions. Machine learning (ML) offers a promising approach to enhance diagnostic accuracy and efficiency.

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Article Synopsis
  • - Primary cilia in pancreatic beta cells are crucial for paracrine signaling, and their dysfunction is linked to diabetes, but their structural functions are not well understood.
  • - Researchers used electron and expansion microscopy to create 3D models of these cilia, revealing they are confined in deep pockets, lack movement components, and have an unstructured organization.
  • - The study identified unique interactions between beta cell cilia and other cells, including specialized connections to cholinergic nerves, emphasizing the importance of cilia in integrating signals that affect islet function in relation to health and diabetes.
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Objectives: To assess the correlation of social determinants of health (SDOH) with the general care patterns related to gastroesophageal reflux disease and laryngopharyngeal reflux. Determine correlation of SDOH on utilization rates for medication, reflux testing and surgical intervention for patients diagnosed with reflux. Describe overall care patterns for gastroesophageal reflux disease care at a tertiary academic facility.

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Article Synopsis
  • Traumatic brain injury (TBI) is prevalent among military personnel and is linked to an increased risk of dementia, with the ADVANCE-TBI study focusing on the neurological effects of major battlefield trauma using blood biomarkers like NfL and GFAP.
  • The study involved 1,145 servicemen and veterans, where TBI was identified in 16.9% of those exposed to major trauma, revealing significant mental health issues such as depression, anxiety, and PTSD, alongside impaired mobility and quality of life.
  • Elevated GFAP levels were found post-TBI, particularly in more severe cases, indicating a correlation with mental health challenges and increased unemployment, demonstrating the long-term impact of TBI on military personnel.
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