Publications by authors named "D R Dossetor"
A better understanding of the endocannabinoid system and a relaxation in regulatory control of cannabis globally has increased interest in the medicinal use of cannabinoid-based products (CBP). We provide a systematic review of the rationale and current clinical trial evidence for CBP in the treatment of neuropsychiatric and neurodevelopmental disorders in children and adolescents. A systematic search of MEDLINE, Embase, PsycINFO, and the Cochrane Central Register of Trials was performed to identify articles published after 1980 about CBP for medical purposes in individuals aged 18 years or younger with selected neuropsychiatric or neurodevelopmental conditions.
View Article and Find Full Text PDFObjective: To determine rates of psychiatric comorbidity in a clinical sample of childhood movement disorders (MDs).
Design: Cohort study.
Setting: Tertiary children's hospital MD clinics in Sydney, Australia and London, UK.
Importance: Selective serotonin receptor inhibitors are prescribed to reduce the severity of core behaviors of autism spectrum disorders, but their efficacy remains uncertain.
Objective: To determine the efficacy of fluoxetine for reducing the frequency and severity of obsessive-compulsive behaviors in autism spectrum disorders.
Design, Setting, And Participants: Multicenter, randomized, placebo-controlled clinical trial.
Background: Tics are conceptualized as a sensorimotor phenomenon with a premonitory urge typically described by patients. As observed in other neurodevelopmental disorders, we have observed sensory dysregulation symptoms, such as tactile hypersensitivity to clothing, in children with tic disorders; however, formal clinical research in this area is limited.
Objective: To define the presence of sensory dysregulation symptoms in tic disorders, and their clinical associations.