Publications by authors named "D R DeYoung"

Article Synopsis
  • The article investigates how patient demographics and factors related to MRI examinations affect patient-reported experiences.
  • A quality improvement study was conducted with over 3,600 outpatient MRI patients, using a post-appointment survey to gather feedback on their experiences.
  • Findings revealed that male patients, shorter exam times, and timely appointments were linked to more positive ratings, while longer wait times and physical discomfort contributed to negative feedback.
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Diffusion MRI (dMRI) has been able to detect early structural changes related to neurological symptoms present in Huntington's disease (HD). However, there is still a knowledge gap to interpret the biological significance at early neuropathological stages. The purpose of this study is two-fold: (i) establish if the combination of Ultra-High Field Diffusion MRI (UHFD-MRI) techniques can add a more comprehensive analysis of the early microstructural changes observed in HD, and (ii) evaluate if early changes in dMRI microstructural parameters can be linked to cellular biomarkers of neuroinflammation.

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Background: Amyotrophic lateral sclerosis (ALS) is a disease characterized by a progressive degeneration of motor neurons leading to paralysis. Our previous MRI diffusion tensor imaging studies detected early white matter changes in the spinal cords of mice carrying the G93A-SOD1 mutation. Here, we extend those studies using ultra-high field MRI (17.

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