Publications by authors named "D R Castaneda"
Article Synopsis
- * A comprehensive literature search found 25 relevant studies indicating that while cervical collars can improve short-term outcomes and pain control for fusion procedures, they do not significantly affect fusion rates.
- * For motion-preserving surgeries like cervical laminoplasty, extended use of collars may lead to increased neck pain and reduced range of motion, suggesting their benefits diminish over time.
Article Synopsis
- - The study investigated the relationship between Tumor Mutational Burden (TMB) and Microsatellite Instability (MSI) status in patients with urothelial carcinoma (UC) receiving immune checkpoint inhibitors (ICI), focusing on overall survival (OS).
- - Results showed that patients with a higher TMB (≥10 mut/Mb) generally experienced longer median OS compared to those with lower TMB, although these differences weren't always statistically significant.
- - Notably, patients treated with maintenance avelumab had a significantly better OS when TMB was high (61 months vs. 17 months for low TMB), indicating potential benefits of ICI based on TMB and MSI status, warranting further investigation.
Objectives: This cross-sectional survey aimed to examine employment characteristics and their associations with employment precarity in two high socioeconomic hardship Chicago neighborhoods.
Methods: We used a community-based participatory approach to develop and administer a survey to residents who perceived their work situations to be precarious.
Results: A total of 489 residents were surveyed.
Absence of SARS-CoV-2 in wildlife of northeastern Minnesota and Isle Royale National Park.
Zoonoses Public Health
September 2024
Aims: We investigated the presence of SARS-CoV-2 in free-ranging wildlife populations in Northeastern Minnesota on the Grand Portage Indian Reservation and Isle Royale National Park.
Methods And Results: One hundred twenty nasal samples were collected from white-tailed deer, moose, grey wolves and black bears monitored for conservation efforts during 2022-2023. Samples were tested for viral RNA by RT-qPCR using the CDC N1/N2 primer set.
Several studies have found that maltreated children show neuropsychological deficits in various cognitive domains such as memory and attention, language, visuospatial skills, emotional regulation, social cognition, and executive functioning. In terms of functional connectivity, abused children show an increased connectivity in the salience network (SN) as opposed to a decreased connectivity within the default (DMN) and executive networks (CEN). Children who suffer maltreatment may develop post-traumatic stress disorder (PTSD), which in turn, can increase psychological and cognitive sequelae.
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