Publications by authors named "D R Buck"

Background: There is an under-reporting of anaesthesia-related safety events. Incident-capturing systems (ICSs) are essential for patient safety monitoring, identifying risks and ongoing opportunities for improvement. After a literature review and assessment of our current ICSs, we concluded that our institution lacked a reliable anaesthesia-specific ICS system, leading to under-reporting of anaesthesia-related safety events.

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Doctor-patient communication is a core competency in medical education, which requires learners to adapt their communication flexibly to each clinical encounter. Although conceptual learning models exist, information about how skilled communication develops over time is scant. This study aims to unpack this process of communication learning and to identify its facilitators.

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  • Cannabinoids from the Cannabis sativa plant, like THC and CBD, have therapeutic benefits, particularly in reducing inflammation, although their exact mechanisms are not fully understood.
  • Research describes four new fluorinated cannabinoids and assesses their biological activity in human microglial cells.
  • Initial results show that while most cannabinoids had little impact on cell metabolism, FCBN and FTHC increased certain inflammatory markers, while SG126 and SG154 inhibited them, opening doors for further studies on these new compounds.
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  • Paediatric patients often show respiratory illness symptoms before surgery, which can heighten the risk of respiratory complications during the perioperative period.
  • A quality improvement initiative was launched to standardize documentation of preoperative respiratory illnesses, aiming to boost accurate documentation from 0% to 90% by March 1, 2023.
  • The introduction of a standardized preoperative illness questionnaire proved successful, achieving a documentation rate of 95% and was adopted by nurses, with plans for electronic implementation across all operating room locations.
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  • The study aimed to find the genetic cause of a rare skeletal Class II malocclusion with gingival hyperplasia in a family over four generations.
  • SNP and exome sequencing identified regions on chromosomes 1, 17, and 19 but were inconclusive, leading to further genome sequencing that revealed a complex rearrangement on chromosome 17 involving portions from chromosome 1.
  • This rearrangement is linked to misregulated genes KCNJ2/KCNJ16, suggesting a genetic basis for the observed phenotype and expanding the understanding of conditions associated with the KCNJ2-SOX9 locus.
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