Publications by authors named "D R Boyd"

Emerging aspects of professionalism within forensic anthropology, while enhancing the scientific foundation and practice for the discipline, have created liminalistic spaces and experiences in education and training, employment, ethics, and identities that reflect the broader transitional status in the discipline as a whole. These liminal states and problems are discussed in terms of their creation, development, and potential for resolution. They are interpreted within a liminal framework which requires navigation through significant changes in roles, status, and identity in forensic anthropology practice.

View Article and Find Full Text PDF

Phospholipid scramblase 1 (PLSCR1) is an antiviral interferon-stimulated gene (ISG) that has several known anti-influenza functions such as interfering with viral nuclear import, regulating toll-like receptor (TLR) 9 and potentiating the expression of other ISGs. However, the exact mechanisms of anti-flu activity of PLSCR1 in relation to its expression compartment and enzymatic activity, and the molecular and cellular mechanisms involved have not been completely explored. Moreover, only limited animal models have been studied to delineate its role at the tissue level in influenza infections.

View Article and Find Full Text PDF
Article Synopsis
  • Breast cancer's complexity necessitates a deeper understanding of cellular diversity to improve treatment methods, particularly by studying genetic variations in its subtypes at a single-cell level.
  • This study integrates single-cell RNA sequencing from various sources, resulting in a diverse dataset of 117 samples, which include different breast cancer subtypes like HR+, HER2+, and TNBC, to analyze similarities and differences across models.
  • Results show that PDX models better reflect patient samples than TNBC cell lines, with therapeutic efficacy linked to subtype proportions, underscoring the importance of these findings for preclinical research decisions in breast cancer treatment development.*
View Article and Find Full Text PDF

The model organism Escherichia coli K-12 has one of the most extensively annotated genomes in terms of functional characterization, yet a significant number of genes, ∼35%, are still considered poorly characterized. Initially genes without known functional understanding were given 'y' gene names. However, due to inconsistency in changing 'y' names to non-'y' names over the years, gene name alone does not provide sufficient information as to the characterization level of genes.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: A non-numeric value encountered

Filename: controllers/Author.php

Line Number: 219

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 219
Function: _error_handler

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: A non-numeric value encountered

Filename: libraries/Pagination.php

Line Number: 413

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 274
Function: create_links

File: /var/www/html/index.php
Line: 316
Function: require_once