Publications by authors named "D R Bergman"
Background: The field of radiation oncology (RO) is frequently overlooked by medical students due to limited exposure during traditional medical school curricula. Initiatives aimed at increasing exposure while creating opportunities for medical student engagement are vital. Here, we present the inception, 1.
View Article and Find Full Text PDFSuccessful pancreatic ductal adenocarcinoma (PDAC) immunotherapy requires therapeutic combinations that induce quality T cells. Tumor microenvironment (TME) analysis following therapeutic interventions can identify response mechanisms, informing design of effective combinations. We provide a reference single-cell dataset from tumor-infiltrating leukocytes (TILs) from a human neoadjuvant clinical trial comparing the granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting allogeneic PDAC vaccine GVAX alone, in combination with anti-PD1 or with both anti-PD1 and CD137 agonist.
View Article and Find Full Text PDFOral vaccination of wildlife against rabies via the distribution of vaccine-laden baits is used widely as a management tool in Europe and North America. Over the past several decades, successful programs have targeted important reservoirs, including coyotes, foxes, raccoon dogs, and raccoons, for prevention and control. However, other species (e.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how prenatal exposure to heavy metals (Lead, arsenic, cadmium, selenium) relates to adverse pregnancy outcomes, particularly focusing on differences between low-risk and high-risk groups of women with varying preterm birth histories.
- 404 women participated, and their blood metal levels were measured, showing significant differences in concentration between low-risk and high-risk groups, with low-risk having higher levels of these metals.
- Despite the findings of elevated metal levels, the study found no significant correlation between these metals and negative pregnancy outcomes, indicating a need for more research to explore the effects of these metals on pregnancy.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a risk factor for cardiovascular disease. However, whether family members of individuals with MASLD also share an increased cardiovascular risk is unknown.
Methods: We created a nationwide multigenerational cohort study identifying all family members of Swedish adults diagnosed with biopsy-proven MASLD (1969-2017) and of matched general population comparators (by age, sex, calendar year, and county of residence).