Tobacco treatment and policies in mental health and substance use treatment facilities in the US.

Background: The prevalence of tobacco use among people with mental health and substance use disorders in the US is high. State- and facility-level factors could be associated with the provision of tobacco treatment and tobacco-free grounds policy in mental health and substance use treatment facilities. We estimated the latest prevalence of, and factors associated with tobacco treatment provision and tobacco-free grounds policies in these facilities.

Longitudinal reconfiguration of multifaceted fish α and β diversity triggered by non-native species invasion in tropic rivers of Hainan Island.

Human-mediated fish invasions have reconfigured the native fish faunas throughout the freshwater ecosystems worldwide. Beyond the well-documented homogenization reported in temperate basins, our knowledge on how multifaceted biodiversity response to fish invasions in tropic rivers remains poorly understood. It is also hanged in doubt that how fish invasions modify the longitudinal patterns of fish faunas under the concept of river continuum.

Exploring the influence of polysaccharide on gastrointestinal stability, drug release and formation mechanism of nanoparticles in Zhimu and Huangbai herb pair decoction.

Natural polysaccharides with multiple biological activities from traditional Chinese medicine (TCM) can be self-assembled. Natural nanoparticles have been found to exist in TCM decoctions. However, the influence of polysaccharides in TCM decoctions on the formation mechanism, drug release and gastrointestinal stability of nanoparticles remains unclear.

Imaging characteristics of pediatric primary thymic lymphoepithelioma-like carcinoma: case reports of four children with a literature review.

Objective: This study aimed to analyze the imaging characteristics of lymphoepithelioma-like carcinoma (LELC) in children's thymi.

Methods: Four pediatric cases of primary thymic LELC confirmed by needle biopsy pathology from our research center were enrolled. All children underwent an enhanced chest computed tomography (CT) examination.

The Role of G-Protein-Coupled Receptor Kinase 4 in Modulating Mitophagy and Oxidative Stress in Cerebral Ischemia-Reperfusion Injury.

Cerebral ischemia-reperfusion injury (CIRI) causes significant neuronal damage through oxidative stress, inflammation, and mitochondrial dysfunction. The G-protein-coupled receptor kinase 4 (GRK4) has been implicated in regulating stress responses in various tissues, but its role in ischemic brain injury remains unclear. In this study, we investigated the role of GRK4 in oxidative stress, inflammation, and mitophagy during CIRI using both in vivo and in vitro models.