Publications by authors named "D Prete"
Parietal Epithelial Cells (PECs) activation and proliferation are common to several distinct forms of glomerulopathies. Due to several stimuli, PECs can change to a progenitor (CD24 and CD133/2) or a pro-sclerotic (CD44) phenotype. In addition, PECs, which are constantly exposed to filtered albumin, are known to be involved in albumin internalization, but how this mechanism occurs is unknown.
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- Anti-phospholipid antibodies nephropathy (aPL-N) is linked to serious kidney complications and is a key factor in anti-phospholipid syndrome, but its long-term outcomes and predictors are not yet well understood.
- A thorough review of studies from February 2006 to January 2024 revealed a strong correlation between aPL-N and increased risks of acute kidney injury (AKI) and chronic kidney disease (CKD)/end-stage kidney disease (ESKD).
- The research indicates that conditions like high blood pressure and specific antibody positivity greatly increase the likelihood of developing aPL-N, highlighting the importance of personalized monitoring and treatment for affected patients.
Background/objectives: Comprehensive conservative management (CCM) is a viable treatment option for elderly patients with end-stage kidney disease (ESKD). However, it involves a significant change in dietary habits, such as adopting a low-protein diet. Therefore, it is crucial to understand its impact on the patient's quality of life (QoL), particularly when compared to hemodialysis (HD).
View Article and Find Full Text PDFManaging mineral bone disease (MBD) could reduce cardiovascular risk and improve the survival of dialysis patients. Our study focuses on the impact of calcium bath exposure in dialysis patients by comparing peritoneal dialysis patients (PD, intervention group) and hemodialysis patients (HD, control group). We assessed various factors, including calcium, phosphorus, magnesium, PTH, vitamin D 25-OH, C-terminal telopeptide (CTX), and FGF-23 levels, as well as the calcium bath six hours before the blood sample and the length of daily calcium exposure.
View Article and Find Full Text PDFAn optical-chemical sensor based on two modified plastic optical fibers (POFs) and a molecularly imprinted polymer (MIP) is realized and tested for the detection of 2-furaldehyde (2-FAL). The 2-FAL measurement is a scientific topic of great interest in different application fields, such as human health and life status monitoring in power transformers. The proposed sensor is realized by using two POFs as segmented waveguides (SW) coupled through a micro-trench milled between the fibers and then filled with a specific MIP for the 2-FAL detection.
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