A German version of the Oral Impacts of Daily Performances-reliability and validity.

Objective: The Oral Impact of Daily Performances (OIDP) is a dental patient-reported outcome measure (dPROM) for the estimation of oral health-related quality of life (OHRQoL) and takes the frequency as well as the severity of problems into account; however, it is not available in German language. The aim of this study was, therefore, to evaluate the reliability and validity of the German version of the OIDP in patients of a private practice.

Material And Methods: Translation of the original OIDP version was performed by a forward-backward process.

Synchronous Onset of Breast and Pancreatic Cancers: Results of Germline and Somatic Genetic Analysis.

Background: Synchronous cancers have occasionally been detected at initial diagnosis among patients with breast and ovarian cancer. However, simultaneous coexistence and diagnosis of breast and pancreas cancer has not previously been reported.

Case Report: Paternal transmission of a germline BRCA2 mutation to a patient who was diagnosed at age 40 with locally advanced breast and pancreas cancer is presented.

A phase 2 randomized trial of paclitaxel and carboplatin with or without panitumumab for first-line treatment of advanced non-small-cell lung cancer.

Introduction: This two-part phase 2 study evaluated the efficacy and safety of panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, combined with carboplatin/paclitaxel in patients with previously untreated advanced non-small-cell lung cancer.

Methods: In part 1, patients were sequentially enrolled to receive paclitaxel 200 mg/m(2) and carboplatin (area under the concentration-versus-time curve, 6 mg/min/ml) plus panitumumab (1.0, 2.

Hi-trees and their layout.

We introduce hi-trees, a new visual representation for hierarchical data in which, depending on the kind of parent node, the child relationship is represented using either containment or links. We give a drawing convention for hi-trees based on the standard layered drawing convention for rooted trees, then show how to extend standard bottom-up tree layout algorithms to draw hi-trees in this convention. We also explore a number of other more compact layout styles for layout of larger hi-trees and give algorithms for computing these.

Phase III, randomized study of the effects of parenteral iron, oral iron, or no iron supplementation on the erythropoietic response to darbepoetin alfa for patients with chemotherapy-associated anemia.

Purpose: Functional iron deficiency may impair response to erythropoiesis-stimulating agents (ESAs) in iron-replete patients with chemotherapy-associated anemia (CAA). This study evaluated whether coadministration of parenteral iron improves ESA efficacy in patients with CAA.

Patients And Methods: This prospective, multicenter, randomized trial enrolled 502 patients with hemoglobin (Hb) less than 11 g/dL who were undergoing chemotherapy for nonmyeloid malignancies.