Publications by authors named "D Polito"
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, accounting for over 9 million deaths annually. The prevalence of CAD continues to rise, driven by ageing and the increasing prevalence of risk factors such as hypertension, diabetes, and obesity. Current clinical guidelines emphasize the importance of functional tests in the diagnostic pathway, particularly for assessing the presence and severity of ischemia.
View Article and Find Full Text PDFArticle Synopsis
- A study evaluated 22 non-professional athletes aged 18-52 post-knee surgery, comparing their cardiovascular parameters and functional capacity before and after surgery using transthoracic echocardiography and cardiopulmonary exercise testing (CPET).
- Results showed a significant increase in resting heart rate after surgery, while blood pressure and lung function measurements remained unchanged.
- Although global work efficiency improved and global wasted work decreased, these changes did not significantly affect exercise performance metrics like peak oxygen consumption post-surgery.
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality, and its incidence has grown within several years, quickly becoming the third leading cause of mortality. The disease is characterized by alveolar destruction, air-trapping, and chronic inflammation due to persistent exposure to a large spectrum of harmful particles. The diagnosis of COPD is made by demonstration of persistent and not fully reversible airflow limitation, and different phenotypes may be recognized based on pathophysiological, clinical, and radiological features.
View Article and Find Full Text PDFChronic obstructive pulmonary disease (COPD) is a significant preventable and treatable clinical disorder defined by a persistent, typically progressive airflow obstruction. This disease has a significant negative impact on mortality and morbidity worldwide. However, the complex interaction between the heart and lungs is usually underestimated, necessitating more attention to improve clinical outcomes and prognosis.
View Article and Find Full Text PDFArticle Synopsis
- The study examined right ventricular (RV) changes in 370 elite athletes during the Tokyo and Beijing Olympics, focusing on differences based on gender and type of exercise (isometric vs. isotonic).
- Isotonic athletes displayed greater RV remodeling with notable differences in size measurements compared to isometric athletes, while males generally had larger RV and right atrium sizes but with lower RV TDI velocities.
- Although RV morphological changes varied by exercise type, functional differences were minimal, with female athletes showing unique RV profiles in terms of specific velocity measurements.