Resolving the design principles that control postnatal vascular growth and scaling.

After birth, tissues grow continuously until reaching adult size, with each organ exhibiting unique cellular dynamics, growth patterns, and (stem or non-stem) cell sources. Using a suite of experimental and computational multiscale approaches, we found that aortic expansion is guided by specific biological principles and scales with the vertebral column rather than animal body weight. Expansion proceeds via two distinct waves of arterial cell proliferation along blood flow that are spatially stochastic, yet temporally coordinated.

Exploring the relationship between air pollution, non-alcoholic fatty liver disease, and liver function indicators: a two-sample Mendelian randomization analysis study.

Background And Aims: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder worldwide, with an increasing incidence in recent years. While previous studies have suggested an association between the air pollutant PM2.5 and NAFLD, there is still considerable debate regarding the existence of a clear causal relationship between air pollution and NAFLD.

Further Validation of the Triarchic Model of Grit Scale (TMGS) in Chinese Adolescents.

The Triarchic Model of Grit Scale (TMGS) was developed as an innovative measurement designed to evaluate general grit levels, encompassing perseverance of effort, consistency of interests, and adaptability to situations within a collectivism culture. The present study was undertaken with the aim of examining the factor structure, measurement invariance, empirical validity, and incremental validity of the TMGS among in a sample of Chinese adolescents ( = 997, 43.4% males, = 16.