Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive and fatal condition that requires early diagnosis, management, and specific treatment. The availability of new disease-modifying therapies has made successful treatment a reality. Transthyretin amyloid cardiomyopathy can be either age-related (wild-type form) or caused by mutations in the TTR gene (genetic, hereditary forms).
View Article and Find Full Text PDFBackground: The relationship between physical activity and coronary artery calcification (CAC) was evaluated in different studies during the last years, although the results were conflicting.
Objective: The main objective of the present systematic review was to assess the association between different levels of physical activity and CAC score estimated by computed tomography (CT).
Methods: This systematic review was performed according to PRISMA guidelines.
Aims: Sex-specific thresholds of aortic valve calcification (AVC) have been proposed and validated in Caucasians. Thus, we aimed to validate their accuracy in Asians.
Methods And Results: Patients with calcific aortic stenosis (AS) from seven international centres were included.