Publications by authors named "D Paydar"
Article Synopsis
- Human cytomegalovirus (CMV) disrupts the antiviral response by depleting the STAT2 transcription factor, which is essential for signaling against viral infections.
- This depletion is mediated by the viral protein E27, which triggers the degradation of STAT2 using cellular mechanisms that involve ubiquitin ligase complexes.
- Structural analyses reveal how E27 mimics host proteins to effectively recruit and degrade STAT2, highlighting a conserved strategy for immune evasion in both rat and mouse models of CMV infection.
A case of proven pheochromocytoma is reported of a patient who presented with attacks of apparent hypotension, pulmonary edema, and myocardial injury with typical ECG and enzyme change. In spite of unmeasurably low peripheral blood pressure recordings during the attack, central aortic pressure was well above 240/140 mmHg. A clinical shocklike state was in effect due to severe arterial vasoconstriction.
View Article and Find Full Text PDFThe clinical, hemodynamic findings and surgical results of forty patients with rheumatic tricuspid stenosis are presented. It is concluded that tricuspid stenosis is a frequent lesion. Its signs should be sought carefully and documented by simultaneous measurements of the right ventricular diastolic and right atrial pressures.
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